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Dengue Vaccine Dengvaxia : World’s first dengue vaccine approved in over 10 countries

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Dengue Vaccine Dengvaxia : World’s first dengue vaccine

  • Sanofi-Pasteur, the vaccines global business unit of Sanofi, announced today that the dengue vaccines have received approval in 14 countries.
  • Following a number of countries–Mexico, Brazil, El Salvador, Costa Rica, Paraguay and the Philippines, the Singapore Health Sciences Authority (HSA) today approved the use of  vaccine, Dengvaxia.
  • The vaccine has been approved for use for the prevention of dengue disease caused by dengue virus serotypes 1, 2, 3 and 4 in individuals aged 12 to 45 years.
  • Dengvaxia works like a “booster” that is more effective in protecting individuals who already have baseline immunity due to a previous dengue infection
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Dengue Vaccine DengvaxiaDengue Vaccine Dengvaxia
  • The World Health Organization (WHO) does not recommend that countries implement a national vaccination program using Dengvaxia
  • When the population to be vaccinated has a prevalence of previous dengue infection below 50 percent.
  • “We’re pleased to see the growing medical and public health recognition for the vaccine,” Su Peing Ng, head of Global Medical Affairs for Sanofi Pasteur
  • WHO objectives for 50 per cent reduction in mortality and 25 per cent reduction in morbidity due to dengue by 2020
  • National medical societies in Indonesia, Brazil and Mexico recently also recommended vaccination with Dengvaxia, a company statement said.
Dengue Vaccine DengvaxiaDengue Vaccine Dengvaxia

  • In the clinical study population 9 years old and older, the dengue vaccine has been documented to prevent two-thirds of dengue cases due to all four serotypes of dengue.
  • The dengue vaccine also prevented 8 of 10 hospitalizations due to dengue and 93% of serious dengue cases like the deadly hemorrhagic form of the disease
  • Over the 25-month study follow-up period of the large-scale efficacy studies conducted in 10 endemic countries in Latin America and Asia.
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